SAPHO被定义为由滑膜炎、痤疮、脓疱病、骨肥厚、骨炎组成的综合征,是一种少见的累及皮肤和骨关节的慢性无菌性炎症。SAPHO综合征的临床特征表现多样化,影像学主要表现为骨肥厚和骨炎,诊断主要依靠其临床特征及影像学表现。新型生物制剂的使用及手术方式的改良为SAPHO综合征的治疗提供了新选择。 SAPHO is defined as a syndrome consisting of synovitis, acne, impetigo, osteomalacia and osteitis and is a rare chronic aseptic inflammation involving the skin and bone joints. SAPHO syndrome clinical features of diverse performance, imaging mainly for bone hypertrophy and osteitis, the diagnosis depends mainly on its clinical features and imaging findings. The use of new biological agents and surgical modalities for the treatment of SAPHO syndrome provides a new choice.