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目的了解我院中药注射剂不良反应(ADR)发生原因。方法通过病例回顾跟踪随访的方式时我院236例ADR在患者、药物、处方及护理等单因素和Logistic回归进行多因素分析。结果236例中药注射剂不良反应主要原因为给药剂量过大,联合用药,输液配制时间过长,老龄患者未作肝肾功能检查,适应症不合理等。结论进一步提高医护人员业务水平,改进处方和护理行为可减少ADR的发生。
Objective To understand the causes of adverse drug reactions (ADR) in traditional Chinese medicine injections in our hospital. Methods A multi-factor analysis of 236 cases of ADR in patients, medications, prescriptions, and nursing factors such as univariate and logistic regression was conducted during the follow-up review. RESULTS: The main adverse reactions of 236 cases of TCM injections were excessive dose, combined use of drugs, infusion preparation time was too long, elderly patients did not perform liver and kidney function tests, and indications were unreasonable. Conclusion The further improvement of the medical staff’s business level and improvement of prescription and nursing behavior can reduce the occurrence of ADR.