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目的 :探讨喉癌微血管密度与喉癌预后的关系。方法 :应用 F8相关抗体以 SABC法对 31例手术切除的喉癌微血管进行定量检测。结果 :微血管在喉癌组织学分级及分型中差异无显著性意义 (P >0 .0 5 ) ,而微血管在 2年后的淋巴结转移组 (10 .2 3± 0 .78)与无淋巴结转移组 (6 .38± 0 .33)中差异有显著性意义 (P <0 .0 5 )。结论 :喉癌间质内微血管生成与淋巴结转移和患者的预后有关。
Objective: To investigate the relationship between the microvessel density of laryngeal cancer and the prognosis of laryngeal cancer. Methods: 31 cases of laryngeal carcinoma microvessel resected by FAB-related antibody were detected by SABC method. Results: There was no significant difference in the microvessel histological classification and classification of laryngeal carcinoma (P> 0.05), while the microvessel in the group of lymph node metastasis after 2 years (10.23 ± 0.78) Metastasis group (6 .38 ± 0.33) in the difference was significant (P <0. 05). Conclusions: The microvessel density in the interstitial of laryngeal carcinoma is related to lymph node metastasis and the prognosis of patients.