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目的分析医院各科室中段尿标本病原菌构成、院内分布及常见病原菌的耐药性,为临床控制感染提供方向性参考。方法对医院2015-2017年中段尿分离出的病原菌数据进行统计分析。结果共分离出病原菌422株,其中革兰阴性杆菌324株(76.8%),革兰阳性球菌49株(11.6%),真菌49株(11.6%)。分离率前5位的病原菌依次为大肠埃希菌、真菌、肺炎克雷伯菌、肠球菌及铜绿假单胞菌。病原菌分离率最高的病区是泌尿外科(110株),分离率最高的菌种是大肠埃希菌(220株)。病原菌对各类抗菌药物表现出不同的耐药性,普遍对磺胺类、头孢和青霉素类抗菌药物耐药率高。结论该院中段尿病原菌耐药性高,不同科室、不同疾病病原菌构成和耐药性存在明显差异,及时分离培养病原菌,根据药敏试验靶向选择抗菌药物,才能更好地控制抗菌药物的耐药性。
Objective To analyze the constitution of urinary specimens, the distribution in the hospital and the resistance of common pathogens in the middle sections of various departments of the hospital to provide direction reference for clinical control of infection. Methods The data of pathogenic bacteria isolated from urine in the hospital from 2015 to 2017 were statistically analyzed. Results A total of 422 pathogens were isolated, of which 324 (76.8%) were Gram-negative bacilli, 49 (11.6%) were Gram-positive cocci and 49 (11.6%) were fungi. The top five isolates were Escherichia coli, fungi, Klebsiella pneumoniae, Enterococcus and Pseudomonas aeruginosa. The highest rate of pathogenic bacteria isolated urology (110 strains), the highest isolation rate of Escherichia coli (220 strains). Pathogens showed different resistance to all kinds of antibiotics, generally high rates of resistance to antibiotics such as sulfonamides, cephalosporins and penicillins. Conclusion The pathogenic bacteria in the middle stage of the hospital have high drug resistance, and the pathogenic bacteria in different departments and different diseases have obvious differences in their composition and drug resistance. The pathogens can be isolated and cultured in time, and the antimicrobial drugs can be controlled better according to the drug susceptibility test. Medicinal properties.