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目的探讨进展期胃癌的治疗方法。方法对新野县人民医院2005年10月至2010年1月收住的7例进展期胃癌行新辅助化疗后行根治性手术治疗患者的资料进行回顾性分析。结果 7例患者均在新辅助化疗后进行了D2根治性手术。无手术相关死亡,术后未见严重手术相关并发症。除1例患者失访外,其余患者现均生存(7～60个月),健康状况良好,复查均未发现局部复发和远处转移。结论新辅助化疗加根治性手术是疗效肯定的治疗手段。新辅助化疗加根治性手术的模式很可能将成为进展期胃癌治疗的新标准。
Objective To explore the treatment of advanced gastric cancer. Methods The data of patients undergoing radical surgery after neoadjuvant chemotherapy in 7 cases of advanced gastric cancer admitted to Xinye County People’s Hospital from October 2005 to January 2010 were retrospectively analyzed. Results All 7 patients underwent D2 radical surgery after neoadjuvant chemotherapy. No surgery-related deaths, no serious surgery-related complications after surgery. Except for one patient lost to follow-up, the rest of the patients are now alive (7 to 60 months) and are in good health. No local recurrence or distant metastasis was found during the follow-up. Conclusion Neoadjuvant chemotherapy combined with radical surgery is a sure therapeutic effect. Neoadjuvant chemotherapy plus radical surgery is likely to be the new standard for the treatment of advanced gastric cancer.