研究已证明微小浓度的内毒素即可对根尖周组织产生明显的损害并导致根尖周的骨破坏[1]。对感染根管中的内毒素的有效降解和清除是影响根管治疗成功的关键。本研究拟探讨不同消毒制剂对根管内毒素的降解作用,探寻适宜的临床应用形式。1材料与方法1.1实验试剂与设备 Studies have shown that small concentrations of endotoxin can cause significant damage to the periapical tissue and lead to periapical bone destruction [1]. The effective degradation and clearance of endotoxin in infected root canal is the key to the successful root canal therapy. This study intends to explore different disinfectants on endotoxin degradation of root canal, to explore the appropriate clinical application form. 1 Materials and Methods 1.1 Experimental reagents and equipment