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目的:考察牛黄清心丸中各单味药对朱砂中汞的溶解性的影响。方法:用阳极溶出伏安法测定可溶性汞的含量。结果:牛黄清心丸中的大多数单味药对朱砂中汞的溶出有抑制作用,但茯苓对朱砂中汞的溶出有显著的促进作用。结论:牛黄清心丸中可溶性汞的浓度比其总汞含量低,汞的不同形态有不同的毒性。因此,仅依据总汞含量来考察汞的毒性是片面的。研究牛黄清心丸中各单味药对朱砂中可溶性汞的影响对了解牛黄清心丸中汞的毒性具有重要意义
Objective: To investigate the effect of each single herb in Niuhuang Qingxin Pills on the solubility of mercury in cinnabar. Methods: The soluble mercury was determined by anodic stripping voltammetry. Results: Most of the single-taste drugs in Niuhuang Qingxin Pills inhibited the dissolution of mercury in cinnabar, but Sb had a significant effect on the dissolution of mercury in cinnabar. Conclusion: The concentration of soluble mercury in Niuhuang Qingxin Pill is lower than its total mercury content. Different forms of mercury have different toxicity. Therefore, examining the toxicity of mercury based on the total mercury content is one-sided. Study on the effect of each single herb in Niuhuang Qingxin Pill on soluble mercury in cinnabar is important for understanding the toxicity of mercury in Niuhuangqing Xinwan