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目的:探讨半夏白术天麻汤祛痰作用与高脂血症相关指标总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)低密度脂蛋白(LDL-C)的关系。方法:取健康成年雄性SD大鼠随机分为空白组、模型组、治疗组;建立高脂血症动物模型,采用推荐酶法(CHOD-PAP法)测定各组大鼠血浆TC,TGHDL-C,LDL-C水平。结果:空白组与模型组对照TC、TG、LDL-C差别有显著统计学意义;模型组与治疗组的TC、TG、LDL-C差别有统计学意义;各组高密度脂蛋白差别无统计学意义。结论:半夏白术天麻汤可降低高脂血症小鼠模型的TC、TG、LDL-C,其治疗痰症与高脂血症效果之间可能存在联系。
Objective: To investigate the effect of Banxiabaizhutianmaitang expectorant and hyperlipidemia related indicators of total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-C) and low density lipoprotein relationship. Methods: Healthy adult male Sprague-Dawley rats were randomly divided into blank group, model group and treatment group. The animal model of hyperlipidemia was established. The levels of TC, TGHDL-C , LDL-C level. Results: TC, TG, LDL-C in the blank group and the model group were significantly different; TC, TG, LDL-C in the model group and the treatment group were significantly different; the differences of HDL in each group were not statistically significant Significance of learning. Conclusion: Banxiabaizhu Tianma Decoction can reduce TC, TG and LDL-C in hyperlipidemic mouse model, and there may be a relationship between its treatment of phlegm and hyperlipidemia.