不久前Seeff等曾报道25例嗜酒者为治疗目的服用扑热息痛时发生了严重肝坏死。本文补充报告2例,这2例嗜酒者所用扑热息痛剂量均远低于以往认为导致健康成人中毒的剂量。例1:男,39岁,因腹痛、恶心和呕吐入院。患 Seeff recently reported that 25 cases of alcohol consumption for the purpose of taking paracetamol, severe liver necrosis occurred. This article complements the report in 2 cases, both of which consumed far less paracetamol than those previously thought to cause toxicosis in healthy adults. Example 1: Male, 39 years old, admitted to hospital for abdominal pain, nausea and vomiting. Suffering