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目的:对儿科常用的治疗消化性溃疡的药物的临床疗效进行分析。方法:选取我院2011年6月~2012年6月间治疗的94例儿童消化性溃疡患者分为2组,每组47例。一组研究对象使用三联疗法治疗,为对照组;一组研究对象在对照组治疗的基础上予以中药方剂进行治疗,为观察组。连续治疗1个月后,对2组研究对象的溃疡愈合率和HP根除率进行比较。对所有研究对象随访1年,统计溃疡的复发率,并进行组间比较。结果:按上述分组进行治疗,并对HP根除率及溃疡愈合率进行组间比较,观察组研究对象的HP根除率为94.6%,愈合率95.2%及均高于对照组(P<0.05);随访1年观察组的溃疡的复发率5.5%,较对照组20.6%的复发率有明显优势,且具有显著差异性(P<0.05)。结论:在儿科消化性溃疡治疗中在传统三联疗法的基础上使用中药方剂能够提高溃疡愈合率,对溃疡的治疗具有重要价值。
OBJECTIVE: To analyze the clinical efficacy of commonly used drugs for treating peptic ulcer in pediatrics. Methods: A total of 94 children with peptic ulcer treated in our hospital from June 2011 to June 2012 were divided into two groups (n = 47 in each group). A group of subjects using triple therapy for the control group; a group of subjects in the control group based on the treatment of traditional Chinese medicine prescription for the observation group. One month after continuous treatment, ulcer healing and HP eradication rates were compared between the two study groups. All subjects were followed up for 1 year, the recurrence rate of ulcer statistics, and comparison between groups. Results: According to the above groups, HP eradication rate and ulcer healing rate were compared between groups. The HP eradication rate and healing rate in the observation group were 94.6% and 95.2%, respectively, which were significantly higher than those in the control group (P <0.05). The follow-up 1-year observation group ulcer recurrence rate of 5.5%, 20.6% of the control group recurrence rate has obvious advantages, and has significant differences (P <0.05). Conclusion: The treatment of peptic ulcer in the traditional triple therapy based on traditional Chinese medicine prescriptions can improve the healing rate of ulcers, the treatment of ulcers of great value.