In order to investigate the response to climate changes in radial growth of Picea crassifolia at the lower tree line in the middle Qilian mountains in northwestern China, relationships of standardized chronologies of annual ring, earlywood and latewood widths with mean monthly temperature and total monthly precipitation were analyzed by ways of correlation and pointer year analyses. The results show that annual ring, earlywood and latewood widths are significantly negatively correlated with mean monthly temperature in June and July. Annual ring and earlywood widths are significantly and positively correlated with total monthly precipitation in March, May and June and negatively correlated with total monthly precipitation in September. Latewood width is less sensitive to climate changes than the width of earlywood and insignificantly sensitive to precipitation. The results of pointer year analysis revealed that when summer temperatures are higher than the mean summer temperature synchronization and the summer precipitation lower than mean summer precipitation synchronization, narrow annual rings are formed. Wide annual rings are formed when summer temperatures are lower than the mean summer temperature synchronization and summer precipitation higher than mean summer precipitation synchronization. The results indicate that more precipitation in the spring and summer is helpful for radial growth while warmer summer restricts radial growth of P. crassifolia at the lower tree line in the middle Qilian mountains. In order to investigate the response to climate changes in radial growth of Picea crassifolia at the lower tree line in the middle Qilian mountains in northwestern China, relationships of standardized chronologies of annual ring, earlywood and latewood widths with mean monthly temperature and total monthly precipitation were analyzed by ways of correlation and pointer year analyzes. The results show that annual ring, earlywood and latewood widths are significantly negatively correlated with the mean monthly temperature in June and July. Annual ring and earlywood widths are significantly and positively correlated with total monthly precipitation in March , May and June and negatively correlated with total monthly precipitation in September. Latewood width is less sensitive to climate changes than the width of earlywood and insignificantly sensitive to precipitation. The results of pointer year analysis revealed that when summer temperatures are higher than the mean summer temperature synchro nization and the summer precipitation lower than mean summer precipitation synchronization, narrow annual rings are formed. in the spring and summer is helpful for radial growth while warmer summer restrictive radial growth of P. crassifolia at the lower tree line in the middle Qilian mountains.