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前房相关性免疫偏离（ＡＣＡＩＤ）是抗原置入前房后诱发的一种系统免疫偏离现象，以迟发性超敏反应受抑为特征。本文介绍了近１０多年来有关ＡＣＡＩＤ现象的实验研究概况，ＡＣＡＩＤ的特征，及其形成机制。ＡＣＡＩＤ形成必须有完整的眼－脾功能轴心，前房的微观环境是诱导ＡＣＡＩＤ的关键，房水中含有多种免疫调节因子，其中最主要的是转化生长因子－β。近年来有实验证明在活体内或培养皿中模拟前房的微观环境诱导ＡＣＡＩＤ能防治葡萄膜炎的发生、发展，给防治人类葡萄膜炎展示了希望的前景。
Anterior chamber-associated immunosorbent (ACAID) is a systemic immune deviation induced by antigen insertion into the anterior chamber and is characterized by suppression of delayed hypersensitivity. This paper presents an overview of the experimental research on ACAID phenomenon in recent 10 years, the characteristics of ACAID and its formation mechanism. ACAID formation must have a complete ocular spleen axis, anterior chamber microenvironment is the key to induce ACAID, aqueous humor contains a variety of immunomodulatory factors, the most important of which is transforming growth factor-β. In recent years, experiments have proved that in vivo or culture dish simulation of the microcirculation of the anterior chamber induced ACAID can prevent the occurrence of uveitis, the development of prevention and treatment of human uveitis shows the hope of the future.