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目的:对3D-CRT放疗同步联合TP方案化疗在中晚期食管癌患者临床治疗中的效果观察。方法:回顾性分析在我院2011年5月-2013年10月实施治疗的中晚期食管癌患者80例,将患者分成两组,其中对照组和观察组患者分别实施三维适形放疗(3D-CRT)及三维适形放疗(3DCRT)同步联合TP方案化疗治疗,对比分析两组患者临床效果及生存率。结果:和对照组相比,观察组患者的临床有效率及1-2年的生存率明显偏高,差异对比显著P<0.05。结论:在中晚期食管癌患者临床治疗中应用3D-CRT放疗同步联合TP方案化疗方案,临床效果显著值得推广。
OBJECTIVE: To observe the clinical effect of 3D-CRT combined with TP regimen in the treatment of advanced esophageal cancer patients. Methods: Eighty patients with advanced esophageal cancer treated in our hospital from May 2011 to October 2013 were retrospectively analyzed. The patients were divided into two groups. The patients in the control group and observation group were treated with three-dimensional conformal radiotherapy (3D- CRT) and three-dimensional conformal radiotherapy (3DCRT) in combination with TP chemotherapy. The clinical effects and survival rates of two groups were compared. Results: Compared with the control group, the clinical effective rate and 1-2 years survival rate in observation group were significantly higher than those in control group (P <0.05). Conclusion: The application of 3D-CRT radiotherapy combined with TP regimen chemotherapy in the treatment of patients with advanced esophageal cancer is worthy of clinical application.