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已明确在哺乳类(包括人),孕酮是支持妊娠所必需的激素,通过抗孕酮可达到抗孕的目的。法国国家医学研究院发明的,由法国优索福药厂合成的RU_(486)是一种孕激素炔诺酮的衍生物,是第一个有效的激素制剂,有较强的抗孕酮活性。生物学和药理学家证明,在啮齿类和猴等动物,当黄体期给予RU_(486)时,可以引起子宫内膜出血或终止妊娠。RU_(486)在人体血浆中消失的
Has been clear in mammals (including people), progesterone is a hormone necessary to support pregnancy, anti-pregnancy by anti-pregnancy can achieve the purpose. RU_ (486) invented by the French National Academy of Medicine and synthesized by the French Youfuofu pharmaceuticals is a progesterone derivatives of norethindrone is the first effective hormone preparations, has a strong anti-progesterone activity . Biology and pharmacologists have shown that in rodents and monkeys and other animals, RU_ (486) given during the luteal phase can cause endometrial bleeding or termination of pregnancy. RU_ (486) disappears in human plasma