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干扰素是一种天然产生和强有力的抗病毒蛋白质。1957年Isaacs和Lindemann发现此物质为病毒干扰的介质,目前还认识到干扰素具有一系列的细胞调节作用。由于供应有限,目前仍阻碍着大规模的实验、现场应用,甚或对临床潜在作用的全面估价。干扰素看来是一类称为细胞素(cytokines)的激素样物质的原型,这类物质是局部有活性的调节糖蛋白,如上皮生长因子、红细胞生成素、破骨细胞激活因子、移动抑制因子和淋巴毒素。干扰素的活力见于几种
Interferon is a naturally occurring and potent antiviral protein. In 1957, Isaacs and Lindemann found that this substance was a viral interference mediator, and now it is also recognized that interferon has a series of cellular regulation functions. Due to limited availability, it is still a hindrance to large-scale experiments, field applications, or even a full assessment of the potential role of the clinic. Interferon appears to be a prototype of a class of hormone-like substances called cytokines that are locally active regulatory glycoproteins such as epidermal growth factor, erythropoietin, osteoclast activators, migration inhibition Factor and lymphotoxin. The vitality of interferon found in several