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目的:研究菊黄上清含片体外抗病毒作用及其对免疫功能的影响。方法:采用细胞培养技术及鸡胚培养法检测菊黄上清含片对病毒的抑制作用;通过观察对小鼠免疫器官质量、网状内皮系统及体液免疫功能的调节作用。结果:对各种病毒致细胞病变均有不同的抑制作用;能增加小鼠免疫器官的质量,提高小鼠网状内皮系统的吞噬指数和吞噬系数,增加小鼠溶血素抗体的生成。结论:菊黄上清含片对呼吸道合胞病毒、副流感病毒Ⅰ型、腺病毒-7所致细胞病变均有不同的抑制作用,对流感病毒甲型京科86-1和流感病毒B/黔防/252/2001感染有较明显的预防和治疗作用,并具有一定调节机体免疫功能的作用。
Objective: To study the antiviral effect of Chrysanthemum supernatant tablets in vitro and its effect on immune function. Methods: The inhibitory effect of chrysanthemum supernatant tablets on the virus was detected by cell culture technique and chicken embryo culture method. The immune function of immune organs was reorganized by observing the regulation of immunological organs, reticuloendothelial system and humoral immunity. Results: It has different inhibitory effect on all kinds of virus cytopathic effect. It can increase the mass of immune organs in mice, increase the phagocytic index and phagocytic index of mouse reticuloendothelial system and increase the production of mouse hemolysin antibody. Conclusion: Chrysanthemum supernatant tablets have different inhibitory effects on the cytopathic effect of respiratory syncytial virus, parainfluenza virus type Ⅰ and adenovirus-7. Influenza virus type A Kejingke 86-1 and influenza virus B / Qian Fang / 252/2001 infection has a more obvious role in the prevention and treatment, and has some role in regulating the body’s immune function.