自发性非外伤性眼球穿孔少见,一般见于角膜感染和化学烧伤而角膜坏死,以及Terrien角膜边缘变性用类固醇治疗者。自发性巩膜穿孔更少见。本文报导一例自发性巩膜溶解引起的双眼隐蔽性穿孔,表现为结膜水肿的病例。病人系49岁白人妇女,双眼有间歇性剧烈刺痛持续已数年,近来感视力模糊。 Spontaneous non-traumatic eyeball perforation rare, generally seen in corneal infection and chemical burns and corneal necrosis, and Terrien corneal edge degeneration treated with steroids. Spontaneous scleral perforation is even more rare. This article reports a case of spontaneous scleral blindness caused by bilateral perforation, the performance of conjunctival edema cases. The patient is a 49-year-old Caucasian woman with intermittent severe stinging in his eyes for several years and recent blurred vision.