大鼠足跖浮肿法,是目前最常用的抗炎药物筛选方法之一。在肿胀度的测定上,容积法较之周长或厚度测定法精确,因而为人们所喜用。本文介绍一种简易的大鼠足容积测量法。 一、实验装置及操作方法 本装置采用连通器原理,将足容器与刻度吸管按下图连结(图),系统中充满0.1％新洁尔灭溶液或稀肥皂水。 调节足容器中的液面高度至标记线A。开启弹簧夹,使刻度吸管中的液面降至标记线B。将大鼠左后肢踝关节周围作上记号,并拉直放入容器,同时慢慢开启 Rat paw edema method, is currently one of the most commonly used anti-inflammatory drug screening methods. In the determination of the degree of swelling, volumetric method compared with the circumference or thickness determination method is accurate, so people like to use. This article describes a simple rat foot volume measurement. First, the experimental device and method of operation The device uses the principle of the communicator, the foot container and scale pipette click the link (Figure), the system is filled with 0.1% benzalkonium bromide solution or dilute soapy water. Adjust the liquid level in the foot container to Mark A Open the spring clip and drop the level in the graduated pipette to mark B. Rat left hind limb around the ankle mark, and straighten into the container, and slowly open