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前瞻性地研究了149例女性急性缺血性卒中的患者内源性性激素变化,年龄47岁～95岁,平均77.2±0.7岁。大部分病例在卒中发生后2周内经CT确诊,其中133例(89％)CT可见大面积梗死灶。应用斯堪的那维亚卒中量表(SSS)评定卒中程度,总分数在0分～58分之间。对照组由80名健康女性组成,无血栓栓塞疾病,未经性激素治疗,年龄在50岁～88岁之间,平均75.3±0.9岁。在卒中后0d～14d(平均2.9±0.2d)抽取患者静脉血,测定17β-雌二醇(SEM)和睾丸素。
A prospective study of 149 women with acute ischemic stroke patients with endogenous sex hormone changes, aged 47 years to 95 years, with an average of 77.2 ± 0.7 years. Most of the cases were diagnosed by CT within 2 weeks after stroke, with 133 (89%) CTs showing massive infarcts. Stroke severity was assessed using the Scandinavian Stroke Scale (SSS) with a total score of 0 to 58. The control group consisted of 80 healthy women with no thromboembolic disease and without sex hormone treatment. The patients were 50 to 88 years old with an average of 75.3 ± 0.9 years. Patient venous blood was drawn from 0 days to 14 days after stroke (mean 2.9 ± 0.2 days), and 17β-estradiol (SEM) and testosterone were measured.