出生缺陷是影响出生人口素质和围产儿死亡的重要因素之一。出生缺陷患病率存在一定的地域差异。出生缺陷的病因目前尚不明确,目前认为主要有遗传和环境因素两大原因,大部分是遗传和环境因素相互作用的结果~([1])。出生缺陷不仅影响儿童的生长发育和生存质量,还给家庭和社会造成沉重的经济负担,给患者及家庭带来难以摆脱的精神痛苦和心理负担。为了解芜湖市出生缺陷发生情况,现将芜湖市2014年度出生缺陷监测结果分 Birth defects are one of the important factors affecting the quality of the birth population and perinatal death. The prevalence of birth defects there are some geographical differences. The etiology of birth defects is not clear at present, mainly because of the genetic and environmental factors are two major reasons, most of them are the result of the interaction between genetic and environmental factors ~ ([1]). Birth defects not only affect children’s growth and quality of life, but also bring heavy financial burden to families and society, and bring mental pain and psychological burden to patients and families that are hard to get rid of. In order to understand the occurrence of birth defects in Wuhu City, now Wuhu City birth defects monitoring results in 2014