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目的探讨肝癌三种治疗方法的临床疗效和不良反应。方法选取120例原发性肝癌患者,根据治疗方法的不同分为微波射频治疗36例(A组)、高强度聚焦超声治疗54例(B组,HI-FU)与传统药物介入治疗30例(C组),比较三组治疗方法的临床疗效。结果 A组与B组患者近期疗效都比较好,均明显高于C组患者(P<0.05)。A组与B组患者的1年和2年生存率明显高于C组患者(P<0.05)。三组患者的主要不良反应为低中度发热、恶心呕吐和上腹痛等,三组对比差异无统计学意义(P>0.05)。结论微波射频治疗肝癌有比较好的临床疗效,安全性好,能降低死亡率。
Objective To investigate the clinical efficacy and adverse reactions of three kinds of liver cancer treatment. Methods A total of 120 patients with primary hepatocellular carcinoma (HCC) were enrolled in this study. Thirty-six patients (group A) underwent microwave radiofrequency ablation and 54 patients (group B, HI-FU) underwent high intensity focused ultrasound C group), to compare the clinical efficacy of three treatment methods. Results The short-term curative effect of group A and group B was better than that of group C (P <0.05). The 1-year and 2-year survival rates of patients in group A and group B were significantly higher than those in group C (P <0.05). The main adverse reactions of the three groups were mild to moderate fever, nausea, vomiting and upper abdominal pain. There was no significant difference between the three groups (P> 0.05). Conclusion Microwave radiofrequency treatment of liver cancer has better clinical efficacy, good safety, can reduce mortality.