将美洲商陆 Phytolacca americana L.根粉末用甲醇室温提取7天,提取物悬浮于水,依次用正己烷、氯仿、乙酸乙酯和正丁醇分配提取。氯仿部位对高浓度葡萄糖诱导的肾小球膜细胞增殖显示强抑制作用。该部位经硅胶柱分离,依次用正己烷、正己烷-乙酸乙酯和甲醇洗脱,得6个部位。活性部位经制 Phytolacca americana L. root powder was extracted with methanol for 7 days at room temperature, and the extract was suspended in water and partitioned and extracted with n-hexane, chloroform, ethyl acetate and n-butanol. Chloroform showed a strong inhibitory effect on high glucose-induced mesangial cell proliferation. This site was separated on a silica gel column and eluted with n-hexane, n-hexane-ethyl acetate, and methanol in order to obtain 6 sites. Active site system