论文部分内容阅读
目的:观察中成药血滞通配合辛伐他汀10mg,治疗高脂血症的临床疗效。方法:将98例确诊为高脂血症患者随机分为两组,治疗组50例用血滞通配合辛伐他汀10mg治疗,对照组48例用辛伐他汀10mg治疗,观察两组治疗前后临床疗效和血脂指标和降脂幅度等变化。结果:两组治疗高脂血症的总有效率无显著差异。但从显效率看,治疗组优于对照组(P<0.05)。两组组内治疗前后血脂变化比较,差异有统计学意义(P<0.05);治疗后组间比较,治疗组降低血总胆固醇、低密度脂蛋白,升高高密度脂蛋白的疗效优于对照组(P<0.05),降低甘油三酯的疗效两组间无显著差异。治疗组降低总胆固醇和低密度脂蛋白的幅度优于对照组,有显著差异(P<0.05)。两组对治疗前后甘油三酯和高密度脂蛋白的调节幅度无明显差异。结论:中成药血滞通配合辛伐他汀降血脂作用明显,较单用辛伐他汀降脂治疗显效率更高,能显著降低血总胆固醇和低密度脂蛋白,且并没有增加显著不良反应,是一种安全、有效的降脂治疗方案。
Objective: To observe the clinical curative effect of Chinese medicine Xuexiao Tong combined with simvastatin 10mg for the treatment of hyperlipidemia. Methods: A total of 98 patients with hyperlipidemia were randomly divided into two groups. 50 cases in the treatment group were treated with Qianqi Tong with simvastatin 10 mg, and 48 cases in the control group were treated with simvastatin 10 mg. Efficacy and blood lipids and lipid-lowering rate and other changes. Results: There was no significant difference between the two groups in the total effective rate of treating hyperlipidemia. However, from the significant efficiency, the treatment group was better than the control group (P <0.05). The difference of blood lipid between the two groups before and after treatment was statistically significant (P <0.05). After treatment, the therapeutic effect of lowering blood total cholesterol, low density lipoprotein and increasing high density lipoprotein in the treatment group was better than that in the control group Group (P <0.05), reduce the efficacy of triglycerides no significant difference between the two groups. Treatment group decreased total cholesterol and low-density lipoprotein amplitude than the control group, a significant difference (P <0.05). There was no significant difference between the two groups in the adjustment of triglyceride and HDL before and after treatment. Conclusion: The blood-stasis syndrome of traditional Chinese medicine combined with simvastatin has significant anti-hyperlipidemic effect, which is more effective than simvastatin with lipid-lowering therapy alone. It can significantly reduce blood total cholesterol and low-density lipoprotein, and does not increase significant adverse reactions, Is a safe and effective lipid-lowering treatment programs.