1 临床资料患者女,29岁。“关节肿痛6年,呕吐腹泻10 d,头痛3d”入院。患者确诊系统性红斑狼疮(SLE)6年,曾服用“强的松,甲氨蝶呤,来氟米特”治疗,病情稳定。患者8个月前妊娠,停用来氟米特和甲氨喋呤。10d前因进食不洁食物出现呕吐、腹泻,伴视物不清,双下肢凹陷性水肿,行剖宫产手术。术后第2天患者出现剧烈头 1 Clinical data Female patient, 29 years old. “Joint swelling and pain of 6 years, vomiting and diarrhea 10 d, headache 3d ” admission. Patients diagnosed with systemic lupus erythematosus (SLE) for 6 years, had taken “prednisone, methotrexate, leflunomide” treatment, stable condition. Patients were pregnant 8 months ago, leflunomide and methotrexate were discontinued. 10d before due to eating dirty food vomiting, diarrhea, with blurred vision, lower limb pitting edema, cesarean section. On the second postoperative day, the patient showed a sharp head