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大鼠在干球温度38～40℃、湿球温度31～32℃的高温仓中受热致死,平 均受热时间215min,平均最高体温41.7℃。主要观察大脑与小脑皮质改变。结果表明,光镜所见锥体细胞和蒲肯野细胞的空泡变性与高尔基器的明显扩张有关,而光镜所见血管周围Virchow-Robin氏间隙扩张的实质是星形胶质细胞足板的明显肿胀。作者认为文献报导在热衰竭时神经细胞的病变较胶质细胞病变严重的观点、只反映了光镜水平的看法,而电镜观察显示星形胶质细胞的改变较神经细胞明显。
Rats in the dry bulb temperature of 38 ~ 40 ℃, wet bulb temperature of 31 ~ 32 ℃ high temperature compartment died of heat, the average heating time 215min, the average maximum body temperature 41.7 ℃. The main observation of the brain and cerebellar cortex changes. The results showed that the vacuolar degeneration of pyramidal cells and Purkinje cells observed by light microscopy was related to the significant expansion of Golgi apparatus. However, the essence of Virchow-Robin’s perivascular space dilation seen by light microscopy was astrocyte foot plate The obvious swelling. The authors suggest that the literature reports that neuronal lesions were more severe than those with glial cells during heat exhaustion and only reflected light microscopic observations, while electron microscopy revealed more changes in astrocytes than in nerve cells.