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目的:探讨不同药物保守治疗胎盘粘连、植入的临床效果。方法:选取该院2008年6月～2012年6月201例胎盘粘连、植入患者的临床资料进行回顾性分析,将其分为A、B、C3组。A组:天花粉蛋白宫颈注射法;B组:甲氨蝶呤静脉注射法;C组:米非司酮口服法。对3组的不良反应、成功率进行比较分析以期能选择更好药物保守治疗的方法。结果:3种方法都有较好的治疗效果,天花粉蛋白宫颈注射法不良反应少,成功率最高,达100.0%。甲氨蝶呤肌内注射法不良反应大,成功率为97.0%,米非司酮口服法成功率为89.6%。结论:药物保守治疗效果显著,其中天花粉蛋白宫颈注射法更安全有效,更人性化,预后良好,应得到临床广泛应用。
Objective: To investigate the clinical effect of conservative treatment of placenta accreta with different drugs. Methods: The clinical data of 201 cases of placenta adhesion and implantation in our hospital from June 2008 to June 2012 were retrospectively analyzed and divided into A, B and C3 groups. Group A: Trichosanthin cervical injection; Group B: methotrexate intravenous injection; Group C: Mifepristone oral administration. On the three groups of adverse reactions, the success rate of comparative analysis in order to choose a better method of conservative treatment of drugs. Results: All the three methods had better therapeutic effect. Trichosanthin injection with less adverse reactions, the highest success rate was 100.0%. Methotrexate intramuscular injection of adverse reactions, the success rate was 97.0%, mifepristone oral success rate was 89.6%. Conclusion: The conservative treatment of drugs is remarkable. The trichosanthin injection is safer, more effective, more humane and has a good prognosis. It should be widely used clinically.