在恶性淋巴瘤时血清铁蛋白浓度增高,其测定值与何杰金病(HD)的临床病期相关。对血清铁蛋白水平与非何杰金淋巴瘤(NHL)临床病理学之间的关系,至今未有充分研究。本文评价血清铁蛋白测定在NHL临床分期中的价值。方法:研究对象为以往无输血无服用铁剂史的65名健康成人(男47,女18)和55例患者,后者包括NHL46例、HD9例。根据患者对治疗的反应分完全缓解(CR)、部份缓解(PR)或无效(NR)3组。CR指治疗后临床表现消失达4周以上;PR指瘤体缩小50%或以上,且4周以上无新病灶出现。结果:47名健康男性和18名健康女性的平均血清 Serum ferritin concentrations increase in malignant lymphomas and correlate with the clinical stage of Hodgkin’s disease (HD). The relationship between serum ferritin levels and the clinical pathology of non-Hodgkin’s lymphoma (NHL) has not been well studied so far. This article evaluates the value of serum ferritin in the clinical staging of NHL. METHODS: The study population consisted of 65 healthy adults (47 males, 18 females) and 55 patients without prior history of transfusions of non-transfused iron, including 46 with NHL and 9 with HD9. Patients were divided into three groups according to their response to treatment: complete remission (CR), partial remission (PR), or ineffectiveness (NR). CR refers to the clinical manifestations disappeared after treatment for 4 weeks or more; PR refers to the tumor reduced by 50% or more, and no new lesions over 4 weeks. Results: Mean serum in 47 healthy men and 18 healthy women