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目的分析哈萨克族受检人群肥胖与代谢综合征的关系。方法对哈萨克族受检人群进行抽样检查,采用氧化酶法测定甘油三酯(TG)、总胆固醇(TC)、空腹血糖(FPG);化学修饰酶法测定高密度脂蛋白胆固醇(HDL-C);直接一步法检测低密度脂蛋白胆固醇(LDL-C)水平。结果哈萨克族受检人群的代谢指标检测,除了高密度脂蛋白水平男性低于女性外,其他指标男性均高于女性,差异有统计学意义(P<0.05)。随着年龄的增加,男性和女性代谢综合征检出率增加。肥胖情况下男性和女性代谢综合征的检出率分别是47.5%和23.3%,男性高于女性,差异有统计学意义(P<0.05)。男性和女性肥胖人群罹患代谢综合征的发病风险分别是正常人群的14.854倍和16.739倍。结论哈萨克族受检人群MS及其代谢组分表现出性别差异和特点,肥胖情况下患病风险急剧增加。因此通过健康教育,减少体重,控制代谢性紊乱以及由其引发的心脑血管疾病发生具有重要的意义。
Objective To analyze the relationship between obesity and metabolic syndrome in Kazakh subjects. Methods The Kazakh subjects were sampled and examined for the determination of triglyceride (TG), total cholesterol (TC) and fasting blood glucose (FPG) using oxidase method. The levels of high density lipoprotein cholesterol (HDL- ; Direct one-step detection of low-density lipoprotein cholesterol (LDL-C) levels. Results The metabolic indexes of Kazakh subjects were higher than those of female except that the level of HDL in males was lower than that in females. The difference was statistically significant (P <0.05). With age, the detection rate of metabolic syndrome in males and females increases. The prevalence of metabolic syndrome in both male and female subjects was 47.5% and 23.3%, respectively, in obese men and higher than in females, with a statistically significant difference (P <0.05). The incidence of metabolic syndrome in obese and male obese people is 14.854 times and 16.739 times of the normal population, respectively. Conclusion MS and its metabolic components of Kazakh subjects showed gender differences and characteristics, and the risk of obesity increased sharply. Therefore, through health education, weight loss, control of metabolic disorders and the cardiovascular and cerebrovascular diseases triggered by it is of great significance.