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目的探讨连续性血液净化(continuous blood purification,CBP)治疗重症胰腺炎合并急性肾功能衰竭的临床疗效。方法选取2009年10月-2011年10月我院血液净化中心收治的重症胰腺炎合并急性肾功能衰竭患者19例,所有患者在行常规治疗的基础上给予CBP治疗,对治疗前后的肾功能、小便量、APACHEⅡ及临床症状等进行对比观察。结果 CBP治疗后患者的心率、呼吸及血淀粉酶等各项指标较治疗前有了明显的好转,尿量增多,逐渐正常。各项指标的改善程度24h<48h。结论连续性血液净化治疗重症胰腺炎合并急性肾功能衰竭患者临床效果显著,改善了患者的预后,并降低了患者的病死率,是治疗重症胰腺炎合并急性肾功能衰竭的有效治疗方法。
Objective To investigate the clinical efficacy of continuous blood purification (CBP) in the treatment of severe pancreatitis complicated with acute renal failure. Methods From October 2009 to October 2011, 19 patients with severe pancreatitis and acute renal failure admitted to our hospital’s blood purification center were enrolled. All patients were given CBP on the basis of routine treatment, Urine volume, APACHE Ⅱ and clinical symptoms such as comparative observation. Results After CBP treatment, heart rate, respiration, blood amylase and other indicators of patients had a significant improvement than before treatment, urine output increased gradually normal. The improvement of the indicators 24h <48h. Conclusion Continuous blood purification for patients with severe pancreatitis complicated by acute renal failure has significant clinical effect, improves prognosis and reduces the mortality of patients. It is an effective treatment for severe pancreatitis with acute renal failure.