论文部分内容阅读
目的:探讨高压氧辅助不同手术超早期治疗基底节脑出血对患者血清血管内皮生长因子(VEGF)、C反应蛋白(CRP)及白介素-6(IL-6)的影响。方法:选取我院2012年2月~2015年1月288例患者进行分组治疗,每组各96例,分别采用高压氧辅助开颅手术、小骨窗外侧裂-岛叶入路与软通道血肿穿刺引流进行治疗,比较患者治疗后3、7、14d后各项指标的变化情况。结果:术前及术后3dA、B、C三组患者并没有显著差异(P>0.05),在治疗后7、14dA、B组患者各项指标均明显低于C组,具统计学意义(P<0.05),A组与B组之间差异不显著(P>0.05)。结论:高压氧辅助超早期骨窗外侧裂-岛叶入路与软通道血肿穿刺引流手术治疗疗效显著,明显优于传统开颅手术治疗,是值得在临床中研究与应用的治疗方法。
OBJECTIVE: To investigate the effects of hyperbaric oxygen on the serum levels of vascular endothelial growth factor (VEGF), C-reactive protein (CRP) and interleukin-6 (IL-6) in patients undergoing ultra- Methods: A total of 288 patients in our hospital from February 2012 to January 2015 were divided into two groups. Each group consisted of 96 patients. Hyperbaric oxygen-assisted craniotomy, lateral fissure-insular approach and soft-passage hematoma puncture Drainage treatment, compare the changes in the indicators after 3,7,14d after treatment. Results: There was no significant difference between the three groups before and after 3dA (P> 0.05). After 7 and 14 days of treatment, the indexes in group A and B were significantly lower than those in group C (P <0.05) P <0.05). There was no significant difference between group A and group B (P> 0.05). CONCLUSION: Hyperbaric oxygen-assisted ultra-early bone-window lateral fissure-insular approach and soft-channel hematoma drainage and drainage surgery have significant curative effect, which is obviously superior to traditional craniotomy. It is worth to be studied and applied in clinic.