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目的总结胎盘早剥晚期早产儿的临床特点与治疗方案。方法从2009年10月至2011年5月从北京军区总医院附属八一儿童医院早产儿重症监护中心患儿资料中,根据入选条件,选取患儿83例,其中胎盘早剥37例为观察组,非胎盘早剥46例为对照组,进行回顾性分析。结果观察指标中,两组患儿比较,胎龄、多胎、胎膜早破史、出生体重、体重与胎龄匹配情况(小于胎龄儿或否)、母亲年龄、母亲妊娠糖尿病、新生儿窒息史、入院时活化部分凝血活酶时间(APTT)、D-二聚体(D-D)、输注悬浮红细胞、输注血浆及使用肝素指标差异有统计学意义(P<0.05)。结论胎盘早剥属于胎盘功能不全,多继发早产儿凝血功能异常,使用小剂量肝素、输注血浆防治效果理想。
Objective To summarize the clinical features and treatment of preterm infants with advanced placental abruption. Methods From October 2009 to May 2011, 83 children were selected according to the selection criteria from 37 children with pre-baby care center at Bayi Children’s Hospital Affiliated to Beijing Military Region General Hospital. Among them, 37 cases of placental abruption , 46 cases of non-placental abruption as control group, for retrospective analysis. Results In the observation indicators, the gestational age, multiple births, the history of premature rupture of membranes, birth weight, body weight and gestational age (less than gestational age or not), mother’s age, mother’s gestational diabetes mellitus, neonatal asphyxia There was significant difference in the history of APTT, DD, infused suspension erythrocyte, infusion of plasma and the use of heparin on admission (P <0.05). Conclusion Placental abruption is placental insufficiency, coagulation dysfunction in multiple secondary preterm children, the use of low-dose heparin infusion plasma control effect is ideal.