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高血压病人可能患充血性心力衰竭、支气管哮喘、糖尿病或肾损害,对此种情况β阻滞剂既不是禁忌药但也不是首选药。在过去的6年凡有上述并发症的欧洲病人均从Estulic(guanfacine hydrochloride)获益,这是由Sandoz公司A H Robins厂生产的一种每日用一次的中枢α_2肾上腺受体促效剂抗高血压药。该药厂已获得在美国生产和出售的许可证,此药的商品名为Tenex。
Hypertensive patients may have congestive heart failure, bronchial asthma, diabetes or kidney damage, in which case beta blockers are neither contraindications nor preferred drugs. In the last 6 years all European patients with these complications have benefited from Estulic (guanfacine hydrochloride), a centrally-administered, once-daily central α 2 -adrenoreceptor agonist produced by the AH Robins plant in Sandoz Blood pressure medicine. The pharmaceutical company has obtained a license to manufacture and sell in the United States under the trade name Tenex.