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虾红素是一种具有很强抗氧化活性的类胡萝卜素,具有诸多生物学功能,如抗炎、免疫调节、抗肿瘤、抗氧化、抗衰老、抗凋亡等。近年来研究发现,虾红素能够有效地调节男性生殖系统中的氧化与抗氧化动态平衡,保护精子线粒体功能,对抗睾丸热应激与生殖毒物的损伤,还可促进精子获能与顶体反应的发生,调节生殖内分泌激素平衡,并在原发性不育、代谢综合征相关的不育中有很好的疗效,对于迟发性性腺功能减退症的治疗与前列腺保健也有一定帮助。本文就虾红素在男性生殖健康中的研究进展进行综述,以期为男性生殖健康问题的预防与治疗提供新的思路。
Astaxanthin is a carotenoid with strong antioxidant activity and has many biological functions such as anti-inflammatory, immune regulation, anti-tumor, anti-oxidation, anti-aging and anti-apoptosis. In recent years, studies have found that astaxanthin can effectively regulate the dynamic balance of oxidation and antioxidation in the male reproductive system, protect the mitochondrial function of sperm, against the damage of testicular heat stress and reproductive toxicants, and also promote sperm capacitation and acrosome reaction , The regulation of reproductive endocrine hormone balance, and primary infertility, metabolic syndrome-related infertility have a good effect, for the treatment of delayed hypogonadism and prostate health also have some help. This review summarizes the research progress of astaxanthin in male reproductive health in order to provide new ideas for the prevention and treatment of male reproductive health problems.