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本文对22例再生障碍性贫血病人因子Ⅷ促凝活性(Ⅷ:C),血管性假性血友病因子(VWF),VWF/Ⅷ:C的血浆水平进行了观察,发现再生障碍性贫血病人Ⅷ:C较正常组明显增高(P<0.01),且与TCO2呈负相关。提示病人Ⅷ;C增高可能与HCO3减少有关。VWF虽略有增高但经统计学处理无显著性差异。VWF/Ⅷ:C较正常组明显减低(P<0.05),是由于Ⅷ:C增高所致。
In this paper, plasma levels of factor Ⅷ procoagulant activity (Ⅷ: C), von Willebrand factor (VWF) and VWF / Ⅷ: C in 22 patients with aplastic anemia were observed and found that patients with aplastic anemia Ⅷ: C was significantly higher than the normal group (P <0.01), and negatively correlated with TCO2. Prompt patient Ⅷ; C increased may be related to the reduction of HCO3. Although VWF slightly increased, but no significant difference by statistical analysis. VWF / Ⅷ: C was significantly lower than the normal group (P <0.05), due to the increase of Ⅷ: C.