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目的探讨完整结肠系膜切除在结肠癌手术治疗中的临床应用效果。方法选取2007年5月—2008年6月结肠癌患者112例为研究对象,随机分为观察组60例,采用完整结肠系膜切除的手术方法;对照组52例,采用传统的结肠癌手术方法。比较两组疗效,并随访1~3年。结果术后吻合口漏率、残端肿瘤残余率、局部复发率、3年存活率观察组分别为1.67%、1.67%、8.33%、71.67%;对照组分别为9.62%、11.54%、30.77%、59.62%。两组比较差异均有统计学意义(均P<0.05)。结论对结肠癌患者采用完整结肠系膜切除的手术方法能够显著提高患者短期存活率,同时能够降低术后吻合口漏发生率、残端肿瘤残余率以及局部复发率,可推广应用。
Objective To investigate the clinical effect of complete mesorectal excision in the surgical treatment of colon cancer. Methods A total of 112 patients with colon cancer from May 2007 to June 2008 were selected as study subjects. They were randomly divided into observation group (60 cases) and complete mesorectal excision. The control group (52 cases) received conventional colon cancer surgery. The efficacy of the two groups were compared and followed up for 1 to 3 years. Results The postoperative anastomotic leakage rate, stump tumor residual rate, local recurrence rate and 3-year survival rate were 1.67%, 1.67%, 8.33% and 71.67% in the observation group and 9.62%, 11.54% and 30.77% in the control group, , 59.62%. The differences between the two groups were statistically significant (P <0.05). Conclusion The operation of complete mesorectal excision in patients with colon cancer can significantly improve the short-term survival rate of patients, reduce the incidence of postoperative anastomotic leakage, stump tumor residual rate and local recurrence rate, which can be extended and applied.