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目的探讨基层医院剖宫产手术抗菌素预防应用的最佳方法。方法随机选择36例剖宫产产妇作为研究组,提取其手术切口分泌物进行细菌培养+药敏试验。选择225例既往在我院行剖宫产的产妇作为对照组。比较两组剖宫产产妇围手术期抗菌药物的选择、用药时间、疗程和联合用药等方面的合理性进行分析。结果 261产妇中应用β-内酰胺类占88.5%,应用克林霉素占3.44%,联合应用甲硝唑占88.5%,全部手术切口分泌物细菌培养阴性,全部产妇手术切口呈甲级愈合。结论现阶段基层医院剖宫产围手术期抗菌药物的应用普遍不合理,加强抗菌药物合理应用的研究和管理仍任务艰巨。
Objective To explore the best way to prevent and treat antibiotics in cesarean section in primary hospitals. Methods 36 cases of cesarean section were randomly selected as the study group, the surgical incision secretions were extracted for bacterial culture + drug sensitivity test. 225 cases of past maternity caesarean section in our hospital as a control group. During the perioperative period, the choice of antibacterials, medication duration, duration of treatment and combination therapy were compared between the two groups. Results Among 261 women, β-lactam accounted for 88.5%, clindamycin (3.44%) and metronidazole (88.5%). All the surgical incision secretions were negative for bacterial culture and all the maternal surgical incisions were Grade A healed. Conclusion The application of perioperative antimicrobial agents in cesarean section in primary hospitals at this stage is generally unreasonable. It is still an arduous task to strengthen the research and management of rational use of antimicrobial agents.