Hepatoid adenocarcinoma of the colon in a patient with inflammatory bowel disease

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:ceshi110
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
A case is presented of a 36-year-old male with primary sclerosing cholangitis-associated inflammatory bowel disease(PSC-IBD) and two synchronous stage 1 adenocarcinomata of the colon,who was initially treated with a subtotal colectomy with ileostomy.One year later,the patient presented with extensive intra-abdominal lymphadenopathy and peritoneal carcinomatosis,as well as a markedly elevated serum level of alpha-fetoprotein(AFP).Fine needle aspiration biopsy of a porta hepatis lymph node revealed a metastatic hepatoid adenocarcinoma.Subsequent review of the previous colectomy specimen showed that one of the previously identified adenocarcinomata had features suggestive of a hepatoid colonic adenocarcinoma.The patient was subsequently treated with a cytotoxic regimen of FOLFOX(oxaliplatin,leucovorin,5-fluorouracil) and bevacizumab,with stable results being achieved after six months.This case presents the first known report of PSC-IBD associated with synchronous typical and hepatoid adenocarcinomata of the colon and highlights the importance of considering hepatoid adenocarcinoma as a differential diagnosis in patients with an increasing serum AFP level. A case is presented as a 36-year-old male with primary sclerosing cholangitis-associated inflammatory bowel disease (PSC-IBD) and two synchronous stage 1 adenocarcinomata of the colon, who was initially treated with a subtotal colectomy with ileostomy. One year later , the patient presented with extensive intra-abdominal lymphadenopathy and peritoneal carcinomatosis, as well as a marked elevated elevated serum level of alpha-fetoprotein (AFP). Fine needle aspiration biopsy of a porta hepatis lymph node revealed a metastatic hepatoid adenocarcinoma. Subsequent review of the previous colectomy specimen showed that one of the previously identified adenocarcinomata had features suggestive of a hepatoid colonic adenocarcinoma. the patient was treated with a cytotoxic regimen of FOLFOX (oxaliplatin, leucovorin, 5-fluorouracil) and bevacizumab, with stable results being achieved after six months.This case presents the first known report of PSC-IBD associated with synchronous typical and hepatoid aden ocarcinomata of the colon and highlights the importance of considering hepatoid adenocarcinoma as a differential diagnosis in patients with an increasing serum AFP level.
其他文献
介绍了波音公司开发的e-Enabling机载软件电子发布与无线传输系统,它代表着飞机电子化发展的趋势。为了解决航空公司大量老旧飞机只能读取软盘的现状,提出了一种基于2G/3G技
城市化水平的不断提高,城市建设速度的加快,城市在不断发展过程中,建筑工程也在不断的增多。建筑工程的不断增多使得建筑行业中涌入了大量的人,这样就使得建筑市场中竞争更加的激
随着时代的变迁、城市的扩张,在我国不少承载着乡土文化和历史记忆的古村落被整体拆迁或是沦为空心村。虽然目前加强古村落保护与开发利用的呼声日益高涨,但实际工作却困难重重
本文提出一种对于CNLPS中对于嵌套结构的论元定位分析模式的初步设想,并对今后的工作提出展望.
本文试图用神经网络的自适应性来实现多项式环上Grobner基计算,首先给出理想同余神经元,理想同余神经网络定义,在此基础上,给出Grobner基计算的神经网络模型和描述性算法.
IETICT 2013, Beijing, China 27th -29th April, 2013 www.ietict.org www.ciict.netThe 2013 IET International Conference on Information and Communications Technolog
近些年,建筑工程行业促进了经济的发展。而在建筑中的裂缝是影响建筑业发展的一大主要原因,建筑中一旦出现裂缝,不仅影响建筑的质量,还会危及人们的安全。因此,研究建筑结构设计中
节能环保理念提出后,我国建筑行业顺应时代发展的需?要,逐步向节能建筑方向发展。?建筑行业发展过程中,加大了对建筑保温施工技术的重视,并得到了相应的提升,在保?证施工质量的同
在我国新农村的建设过程中,村镇建设是非常重要的组成部分,对和谐社会的构建有着非常重要的意义,所以说,要中分的重视村镇建设规划管理工作,在实践的过程中不断的总结和学习,从而促
BACKGROUND: There is an increasing frequency of pancreaticoduodenectomy(PD) and PD with superior mesenteric-portal vein(SMPV) resection in elderly cancer patien