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用本室制备的对胃癌、结肠癌和肺癌选择较强的单克隆抗体MG7、MG9、MC3及MC5对321例次胸腹水的脱落细胞进行免疫细胞化学检杳。结果表明,用本法检查胸腹水中相应肿瘤细胞,反应灵敏、阳性率高、特异性强、结果可靠。若结合常规病理细胞学检查,对于不典型癌细与异型间皮细胞的鉴别,提高了胸腹水相应癌细胞的阳性检出率,以及推测胸腹水癌细胞的器官来源有较大的价值.尤其适用于解决临床疑难病例的诊断。
Using the monoclonal antibodies MG7, MG9, MC3, and MC5, which were prepared in this laboratory for gastric cancer, colon cancer, and lung cancer, immunohistochemical examination of 321 cases of exfoliative cells in the inferior pleural effusion was performed. The results showed that using this method to check the corresponding tumor cells in the thoracic and abdominal water, the reaction was sensitive, the positive rate was high, the specificity was strong, and the result was reliable. If combined with routine pathological cytology, identification of atypical carcinoma fine and heterotypic mesothelial cells will increase the positive detection rate of thoracic and ascitic fluid-corresponding cancer cells, and speculate that the source of organs of thoracic and ascitesal cancer cells is of great value. It is suitable for the diagnosis of clinically difficult cases.