论文部分内容阅读
目的:对2012年1月—2014年12月我县恰卜恰镇区1 505名(3~6)岁幼托儿童采集血清标本,检测乙肝病毒表面抗体(抗-HBs)阳性率水平,了解免疫接种乙肝疫苗后产生乙肝病毒表面抗体(抗-HBs)的阳性率,以便及时补种,为防止乙肝制定科学的免疫策略提供依据。方法:对所有监测儿童采集静脉血5mL,采用酶联免疫吸附试验法检测乙肝病毒表面抗体(抗-HBs)。结果:1 505名儿童中,抗-HBs阳性973人,阳性率为64.65%,不同年龄组间阳转率有显著性差异,男女性别间没有显著性差异。结论:为了更好地预防乙型肝炎的传播,应加强托幼园所卫生保健,家长要高度重视乙肝疫苗注射,一定要按程序接种和复种乙肝疫苗,这样才能更有效地控制乙肝病毒感染;同时对入托前儿童定期进行乙型肝炎表面抗体检测,以便及时注射乙肝疫苗。
OBJECTIVE: To collect serum samples from 1 505 (3-6 years old) preschool children in QiaBuqia town from January 2012 to December 2014 to detect the positive rate of hepatitis B virus surface antibody (anti-HBs) The positive rate of hepatitis B virus surface antibody (anti-HBs) after immunization with hepatitis B vaccine in order to replant in time to provide a basis for preventing hepatitis B from formulating a scientific immunization strategy. Methods: 5 mL of venous blood was collected from all the monitored children, and HBsAg was detected by enzyme linked immunosorbent assay (ELISA). Results: Of the 1 505 children, 973 were positive for anti-HBs, with a positive rate of 64.65%. There was a significant difference in the rate of positive conversion between different age groups. There was no significant difference between male and female gender. Conclusion: To better prevent the spread of Hepatitis B, heath care facilities should be strengthened. Parents should attach great importance to the injection of Hepatitis B vaccine. Hepatitis B vaccine must be vaccinated and multiplexed according to the procedure in order to control the Hepatitis B virus infection more effectively. At the same time on a regular basis to children before enrollment hepatitis B surface antibody testing, in order to timely injection of hepatitis B vaccine.