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目的:探讨心力衰竭(心衰)患者肺部超声B线的数量和血浆氨基末端脑钠肽前体(NT-proBNP)浓度对心衰的诊断价值。方法:选取2014年3-9月就诊于苏州大学附属第一医院急诊或住院的心衰患者59例(男39例,女20例),均行床旁超声心动图、肺部超声检查及血浆NT-proBNP浓度的测定。结果:B线数量及血浆NT-proBNP水平随NYHA心功能严重程度而增加,差异有统计学意义(P<0.05)。B线与血浆中NT-proBNP水平呈明显的正相关关系(r=0.65,P<0.01)。B线诊断NYHA心功能Ⅱ级以上心衰的ROC曲线下面积为0.702,NT-proBNP诊断NYHA心功能Ⅱ级以上心衰的ROC曲线下面积为0.685。结论:床旁肺部超声是评估心衰的一种新的手段,联合血浆NT-proBNP水平可提高对心衰的诊断价值。
Objective: To investigate the value of pulmonary ultrasound B-line and the concentration of plasma NT-proBNP in patients with heart failure (CHF) for the diagnosis of heart failure. Methods: 59 patients (39 males and 20 females) with heart failure admitted to the First Affiliated Hospital of Soochow University from March to September 2014 were enrolled. All patients underwent echocardiography, ultrasonography and plasma Determination of NT-proBNP concentration. Results: The number of B line and plasma NT-proBNP level increased with the severity of NYHA cardiac function, the difference was statistically significant (P <0.05). B line and plasma NT-proBNP level was significantly positive correlation (r = 0.65, P <0.01). The area under the ROC curve of line B diagnosed with heart failure above NYHA level II was 0.702. The area under the ROC curve of NT-proBNP in diagnosing heart failure above NYHA level II was 0.685. Conclusion: Bedside pulmonary ultrasound is a new measure of heart failure. Combined with plasma NT-proBNP level can improve the diagnostic value of heart failure.