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日前,FDA公告称抗癫痫药物氯巴占(clobazam,Onfi)能诱发罕见且致死性皮肤反应。本品于2011年经FDA批准作为一款辅助药物用于伴有兰诺克斯综合征的癫痫治疗。本品引起的皮肤反应为史蒂文斯-约翰逊综合征(SJS)和中毒性表皮坏死松解症(TEN)。症状和体征包
Recently, the FDA announced that the anti-epileptic drug clobazam (Onfi) can induce a rare and lethal skin reaction. This product was approved by the FDA in 2011 as an auxiliary drug for the treatment of epilepsy associated with Lanos’s syndrome. The skin reaction caused by this product is Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Symptoms and signs package