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肿瘤的发生是多基因参与的过程。大肠癌的发生发展可存在较长的癌前期阶段 ,包括大肠粘膜上皮的增长、息肉性增生或腺瘤及伴有不同程度的不典型增生、癌变、原位癌、浸润癌及转移癌等明显的阶段性形态学上的改变 ,随着分子生物技术的发展 ,表明与其形态学相应的分子生物学改变?
The occurrence of cancer is the process of multiple genes involved. The occurrence and development of colorectal cancer may have a longer precancerous stage, including the growth of large epithelial mucosal epithelium, polyposis or adenoma, and with varying degrees of atypical hyperplasia, cancerous, carcinoma in situ, invasive and metastatic cancers, etc. The phased morphological changes, along with the development of molecular biotechnology, suggest that molecular biology changes corresponding to their morphology?