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为探讨肝硬化发展成肝细胞癌(HCC)的危险因素,作者对613例不同病因类型的肝硬化病人作了前瞻性研究。其中240例酒精性肝硬化中(3例HBsAg阳性),10例发展成HCC;130例原发性胆汁型肝硬化中(1例HBsAg阳性),6例转成HCC;161例慢活肝中(43例HBsAg阳性),16例转成HCC;41例潜隐型肝硬化中(HBsAg均阴性),转成HCC8例;其他型肝硬化41例(全部HBsAg阴性),2例转成HCC。这42例HCC中36例(86%)是男性,平均年龄为55±10岁(22～63岁)。42例HCC中9例
To investigate the risk factors for the development of cirrhosis into hepatocellular carcinoma (HCC), we prospectively studied 613 patients with cirrhosis of different etiology. Of the 240 patients with alcoholic cirrhosis (3 with HBsAg positive), 10 developed HCC; 130 with primary biliary cirrhosis (1 with HBsAg positive), 6 with HCC, 161 with chronic liver disease (43 cases of HBsAg positive), 16 cases turned into HCC; 41 cases of latent liver cirrhosis (negative for HBsAg), turned into HCC8 cases; 41 cases of other cirrhosis (all HBsAg negative), 2 cases turned into HCC. Of these 42 HCCs, 36 (86%) were males with an average age of 55 ± 10 years (22-63 years). 42 cases of HCC in 9 cases