肝切除被认为是治疗肝细胞肝癌最有效的方法 ,其手术死亡率已下降到 0 % 10 % 〔15〕 ,切除后 5年生存率已达 30 % 50 % 〔5〕。但是切除的远期疗效尚不能令人满意 ,主要是因为切除后有较高的复发率 (术后 5年复发率接近 85% 〔5〕)。尽管目前没有好的方法来预防肿瘤的复发 Liver resection is considered to be the most effective method for the treatment of hepatocellular carcinoma. The operative mortality rate has dropped to 0% 10% [15], and the 5-year survival rate after resection has reached 30% 50% [5]. However, the long-term effect of resection is not satisfactory, mainly because of the higher recurrence rate after resection (5 years after recurrence rate is close to 85% [5]). Although there is currently no good way to prevent tumor recurrence