血管内皮损伤与动脉粥样硬化(简称AS)关系密切,许多因素能损伤内皮促进血脂在动脉壁沉积。免疫机制便是一个重要因素。自从Roberts等报道了血清病可加重实验性胆固醇性AS的发生以来,免疫性血管损伤在AS中的地位已受到人们重视。 Vascular endothelial injury and atherosclerosis (referred to as AS) are closely related, many factors can damage the endothelium to promote blood lipid deposition in the artery wall. Immune mechanism is an important factor. Since Roberts et al reported that serum sickness can aggravate the occurrence of experimental cholesterol AS, the status of immune vascular injury in AS has drawn great attention.