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目的探讨终末期肾病老年患者采用血液透析或腹膜透析治疗的生存预后情况及其影响因素。方法 2010年4月至2014年4月我院收治的192例终末期肾病老年患者,均采用血液透析或腹膜透析进行治疗,观察患者治疗结局,计算生存率。采用Logistic回归分析患者生存率的影响因素。结果 192例患者中死亡59例(30.73%),生存133例(69.27%)。生存患者与死亡患者在年龄、原发性疾病、透析时间、血清白蛋白(Alb)、血糖(GLU)、血清白蛋白(Alb)、高密度脂蛋白(HDL)及高敏C反应蛋白(hs-CRP)水平方面差异均有统计学意义(P<0.05)。Logistic回归分析发现,年龄、原发性疾病、透析时间、Hb、GLU、Alb以及hs-CRP水平均是终末期肾病老年患者血液透析和腹膜透析生存率的影响因素。结论终末期肾病血液透析和腹膜透析老年患者死亡率较高,影响患者生存率的因素较多,临床上根据患者个人情况针对性进行干预,可有效提高终末期肾病患者生存率。
Objective To investigate the survival and prognosis of elderly patients with end-stage renal disease treated with hemodialysis or peritoneal dialysis and its influencing factors. Methods From April 2010 to April 2014, 192 elderly patients with end-stage renal disease were treated by hemodialysis or peritoneal dialysis in our hospital. The treatment outcome was observed and the survival rate was calculated. Logistic regression analysis of the influencing factors of patient survival rate. Results Among the 192 patients, 59 (30.73%) died and 133 (69.27%) survived. Survival patients and death patients were significantly different in age, primary disease, dialysis time, Alb, GLU, Alb, HDL and hs- CRP levels were statistically significant (P <0.05). Logistic regression analysis showed that age, primary disease, dialysis time, Hb, GLU, Alb and hs-CRP levels were both the influential factors of hemodialysis and peritoneal dialysis survival rates in elderly patients with end-stage renal disease. Conclusions The mortality rate of elderly patients with end stage renal disease due to hemodialysis and peritoneal dialysis is high. There are many factors that affect the survival rate of patients. Clinically, according to the individual circumstances of patients, the intervention can effectively improve the survival rate of patients with end-stage renal disease.