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目的评价维吾尔文版癌症患者生命质量测定量表体系共性模块QLICP-GM量表的信度和效度。方法通过量表的翻译、回译及文化调适等制定维吾尔文版癌症患者生命质量QLICP-GM量表,对497例维吾尔族恶性肿瘤患者进行生命质量测试,分析该量表的内部一致性、重测信度、内容效度、区分效度和结构效度等。结果总量表Cronbach’sα系数为0.798,其中基本生理功能、性功能、独立功能、情绪、认知功能、社会支持、对生活/经济影响、副作用、共性症状9个领域的Cronbach’sα系数为0.769～0.823;量表的分半信度为0.71;第1次与第2次测试的重测相关系数为0.367～0.810(均P<0.05),2次测试各领域平均分比较,差异均无统计学意义(P>0.05),提示该版本量表具有较好的重测信度;相关分析结果表明,各领域得分与所属领域得分间的相关性较高(均r>0.7),与其他领域得分间的相关性较小(均r<0.1),提示该量表具有较好的区分效度;经因子分析,量表可归为基本生理功能、性功能、独立功能3个主因子,累积方差贡献率为60.607%,各主因子中各条目与其主成分大致相符;反应度分析表明,第1次与第3次测试的平均分比较,性功能、独立功能、情绪、副作用、共性症状领域间差异均有统计学意义(P<0.05),尚需增大样本量作进一步研究。结论维吾尔文版癌症患者生命质量QLICP-GM量表具有良好的信度和效度,可作为新疆维吾尔族癌症患者生命质量的测评工具。
Objective To evaluate the reliability and validity of the QLICP-GM scale in the Uygur version of the Cancer Patient Quality of Life Scale. Methods The QLICP-GM scale of quality of life of Uighur cancer patients was established by translation, back translation and cultural adjustment of scale, and 497 Uygur patients with malignant tumors were tested for quality of life. The internal consistency and weight Test reliability, content validity, discriminant validity and structural validity. Results The Cronbach’sα coefficient of the total scale was 0.798. The Cronbach’s α coefficient of nine domains of basic physiological function, sexual function, independent function, emotion, cognitive function, social support, life / economic impact, side effects and common symptoms were 0.769 ~ 0.823, respectively; the semi-reliability of the scale was 0.71; the correlation coefficient between the first and the second test was 0.367 ~ 0.810 (all P <0.05) (P> 0.05), suggesting that this version of the scale has a good test-retest reliability; correlation analysis showed that the correlation between scores in each field and their field scores were higher (all r> 0.7), and other (All r <0.1), suggesting that the scale has a good discriminative validity; by factor analysis, the scale can be divided into three main physiological functions, sexual function, independent function of the three main factors, The cumulative variance contribution rate was 60.607%, and each item in each main factor was roughly consistent with its main component. Reactivity analysis showed that the average scores of the first and the third test were: sexual function, independent function, emotion, side effects, common symptoms There were significant differences between the fields (P <0.05), still need to increase Sample size for further study. Conclusion The quality of life QLICP-GM scale of Uighur cancer patients has good reliability and validity and can be used as a measure of quality of life for cancer patients in Uigur.