HIV与其细胞靶间的相互作用曾被认为相当简单:病毒附着于细胞表面的CD_4分子,进入细胞并开始其复制周期,但是在过去的几年里,研究发现了惊人的证据,表明病毒尚可通过非CD_4受体与细胞结合。此时,病毒与Fc受体形成复合物,这些受体包括大脑和肠细胞上的半乳糖神经酰胺,通过与Fc受体的结合使病毒感染增强。 The interaction between HIV and its cellular targets has been thought to be fairly simple: the virus attaches to the cell surface CD 4 molecules, enters the cell and begins its replication cycle, but in the past few years the study found striking evidence that the virus is still Binds to cells via non-CD 4 receptors. At this point, the virus forms complexes with Fc receptors, including galactosylceramide on the brain and intestinal cells, which enhances viral infection through binding to Fc receptors.