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目的:探讨早产儿感染与血清白蛋白之间的相关性。方法:选择我院2014年1-12月收治住院的早产儿200例,分为感染组及非感染组,测定两组的血清前白蛋白、白蛋白、总蛋白水平及感染指标如血常规白细胞、血小板及超敏C反应蛋白(hs CRP)。感染组早产儿在感染治疗好转后再次留取股静脉血清检测白蛋白水平。结果:两组早产儿在胎龄、体质量、血常规(白细胞、血小板)方面比较差异无统计学意义,但两组前白蛋白、白蛋白、总蛋白及hs CRP水平比较差异有统计学意义(P<0.05)。早产儿低蛋白血症的发病率在感染组与非感染组中差异有统计学意义(P<0.05)。感染组早产儿的血清白蛋白在感染治疗前后差异有统计学意义(P<0.05),经治疗感染好转后,感染组早产儿血清白蛋白水平明显升高。结论:早产儿生后血清白蛋白水平可能与是否容易发生感染有关,若早产儿生后白蛋白水平低,应该积极予以补充,以降低其感染几率。
Objective: To investigate the correlation between serum prealbumin and premature infant infection. Methods: A total of 200 preterm infants hospitalized from January to December 2014 in our hospital were divided into infected group and non-infected group. Serum prealbumin, albumin, total protein and infection indexes such as blood leukocyte , Platelets and high-sensitivity C-reactive protein (hs CRP). Infected group of premature children in the infection after the treatment again to take femoral vein serum albumin levels. Results: There was no significant difference in gestational age, body weight and blood routine (leukocyte, platelet) between two groups of preterm infants, but there was significant difference in prealbumin, albumin, total protein and hs CRP between the two groups (P <0.05). The incidence of hypoalbuminemia in preterm children was significantly different between infected and noninfected (P <0.05). Serum albumin in preterm infants in infected group had significant difference before and after infection (P <0.05). Serum albumin levels in preterm infants in infected group were significantly increased after treatment of infection improved. Conclusion: The serum albumin level of premature infants may be related to their susceptibility to infection. If the level of albumin after prenatal infants is low, they should be actively replenished to reduce their chance of infection.