论文部分内容阅读
目的研究超敏C反应蛋白与青年脑梗死颈动脉硬化的相关性。方法对2014年1月—2015年9月在平煤神马医疗集团总医院神经内科住院的120例年龄小于45岁的青年脑梗死患者进行血清超敏C-反应蛋白(hs-CRP)水平的测定以及颈动脉彩超的检查,并且与对照组进行比较。结果 (1)青年脑梗死组的颈动脉斑块发生率及hs-CRP水平均高于对照组,两组间的差异具有统计学意义(P<0.05)。(2)在120例青年脑梗死中,hs-CRP在稳定斑块组和不稳定斑块组含量要高于无斑块组,差异具有统计学意义(P<0.05);hs-CRP在不稳定斑块组的含量高于稳定斑块组,差异具有统计学意义(P<0.05)。结论血清hs-CRP水平与青年脑梗死患者颈动脉粥样硬化的发生有一定相关性,hs-CRP的水平反映了青年脑梗死颈动脉硬化的稳定性,监测血清hs-CRP含量可对青年脑梗死患者的病情严重程度及预后做一个预测。
Objective To investigate the relationship between hypersensitive C-reactive protein and carotid atherosclerosis in young patients with cerebral infarction. Methods Serum levels of hs-CRP were measured in 120 young patients younger than 45 years of age who were hospitalized in the Department of Neurology, Pingdingshan Shenma Medical Group General Hospital from January 2014 to September 2015 Assays and carotid ultrasonography were performed and compared with controls. Results (1) The incidence of carotid artery plaque and the level of hs-CRP in the cerebral infarction group were higher than those in the control group, with statistical significance (P <0.05). (2) The content of hs-CRP in stable plaque group and unstable plaque group was higher than that in non-plaque group in 120 cases of young cerebral infarction, the difference was statistically significant (P <0.05); hs-CRP was not The content of stable plaque group was higher than that of stable plaque group, the difference was statistically significant (P <0.05). Conclusion The level of serum hs-CRP has some correlation with the occurrence of carotid atherosclerosis in young patients with cerebral infarction. The level of hs-CRP reflects the stability of carotid atherosclerosis in young patients with cerebral infarction. Predict the severity and prognosis of patients with infarction.